Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505672 | 0.86 | NR1H4 (0.55) | NR1H4FOLH1RXRANR4A2PDE4B | |
| SCHEMBL369806 | 0.85 | EGFR (0.45) | PPARGMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2772423 | 0.80 | NR1H4 (0.62) | NR1H4RXRARARBPPARGALDH1A1 | |
| SCHEMBL29396992 | 0.80 | NR1H4 (0.62) | NR1H4RXRARARBPPARGALDH1A1 | |
| SCHEMBL370920 | 0.80 | MYC (0.54) | FOLH1PPARGMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5483884 | 0.78 | NR1H4 (0.60) | NR1H4RXRARARBPPARGALDH1A1 | |
| Hydrochloric Acid SCHEMBL5753150 | 0.78 | NR1H4 (0.60) | NR1H4RXRARARBPPARGALDH1A1 | |
| SCHEMBL12505674 | 0.76 | FOLH1 (0.57) | FOLH1RXRARARBBCL2MEN1 | |
| SCHEMBL12505679 | 0.76 | POLB (0.46) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL6546459 | 0.75 | PDCD1 (0.43) | FOLH1ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |