Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370726 | 0.86 | MYC (0.45) | MYCKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17020099 | 0.85 | CXCR5 (0.53) | MYCKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10535282 | 0.84 | CLCN2 (0.48) | MYCSYKHTTFOLH1 | |
| SCHEMBL3391070 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL5720757 | 0.80 | MYC (0.65) | MYCKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL365326 | 0.80 | NR1H4 (0.48) | ALDH1A1MCL1KMT2APPARGPOLB | |
| SCHEMBL1840140 | 0.78 | MCL1 (0.41) | MYCKDM4EALDH1A1CXCR5MCL1 | |
| SCHEMBL12505672 | 0.77 | NR1H4 (0.55) | MCL1PPARGAKR1C3AKR1C2PTGER1 | |
| SCHEMBL656 | 0.77 | MYC (0.71) | MYCKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30755384 | 0.77 | MYC (0.71) | MYCKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |