Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655217 | 0.85 | SMN1; SMN2 (0.47) | BCL2L1NPC1GAAMAPTRAB9A | |
| SCHEMBL3648116 | 0.84 | BCL2L1 (0.49) | BCL2L1NPC1GAAMAPTRAB9A | |
| SCHEMBL3001733 | 0.78 | MEN1 (0.65) | BCL2L1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3001736 | 0.78 | MEN1 (0.65) | BCL2L1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2625445 | 0.74 | BCL2L1 (0.60) | BCL2L1NPC1GAAMAPTRAB9A | |
| SCHEMBL3649157 | 0.73 | GAA (0.54) | NPC1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3010261 | 0.72 | BCL2L1 (1.00) | BCL2L1 | |
| SCHEMBL3010256 | 0.72 | BCL2L1 (1.00) | BCL2L1 | |
| SCHEMBL3777067 | 0.71 | MAPT (0.52) | BCL2L1NPC1GAAMAPTRAB9A | |
| SCHEMBL2997201 | 0.71 | BCL2L1 (1.00) | BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193127-A1 | BENZOTHIAZOLE COMPOUNDS | The Walter and Eliza Hall Institute of Medical Research (AU) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009039553-A1 | BENZOTHIAZOLE COMPOUNDS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2009-04-02 | — | — | WO | disclosed |