⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031230 | 0.77 | NOTUM (0.30) | — | |
| SCHEMBL21161318 | 0.76 | CES2 (0.31) | — | |
| SCHEMBL13822799 | 0.72 | — | — | |
| SCHEMBL15780660 | 0.72 | FABP3 (0.32) | — | |
| SCHEMBL3374348 | 0.65 | — | — | |
| SCHEMBL3649568 | 0.64 | POLB (0.33) | — | |
| SCHEMBL10713168 | 0.64 | — | — | |
| SCHEMBL22290 | 0.63 | — | — | |
| Water SCHEMBL2344271 | 0.63 | POLB (0.33) | — | |
| SCHEMBL17503288 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101765659-A | Method for producing L-lysine | AJINOMOTO KK | 2010-06-30 | — | — | CN | claimed |
| WO-2022166845-A1 | PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 赛诺哈勃药业（成都）有限公司 | 2022-08-11 | — | — | WO | disclosed |
| CN-101765659-B | Method for producing L-lysine | AJINOMOTO KK | 2014-09-24 | — | — | CN | disclosed |
| CN-101765659-A | Method for producing L-lysine | AJINOMOTO KK | 2010-06-30 | — | — | CN | disclosed |
| EP-2197552-A2 | NOVEL TETRAHYDROFUSEDPYRIDINES AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2010-06-23 | — | — | EP | disclosed |
| CN-100506825-C | Heterotricyclyl 6-alkylidene-penems as beta epsilontaualpha-lactamase inhibitors | WYETH CORP (US) | 2009-07-01 | — | — | CN | disclosed |
| WO-2009037001-A2 | NOVEL TETRAHYDROFUSEDPYRIDINES AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2009-03-26 | — | — | WO | disclosed |
| CN-101189010-A | Tricyclic 6-alkylidene-penems as class D beta-lactamase inhibitors | WYETH CORP (US) | 2008-05-28 | — | — | CN | disclosed |
| CN-1649882-A | Heterotricyclyl 6-alkylidene-penems as beta epsilontaualpha-lactamase inhibitors | WYETH CORP (US) | 2005-08-03 | — | — | CN | disclosed |