Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366370 | 0.88 | EGFR (0.43) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL367763 | 0.88 | BAZ2B (0.45) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL364264 | 0.86 | MAPT (0.46) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL367329 | 0.85 | BAZ2B (0.47) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL365258 | 0.84 | KDM4E (0.42) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL365916 | 0.82 | KDM4E (0.40) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL366810 | 0.80 | PTGS2 (0.45) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL365634 | 0.80 | CES1 (0.38) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL367200 | 0.78 | KDM4E (0.55) | EGFRKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL366487 | 0.78 | MAPT (0.50) | EGFRKDM4EMEN1APAF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |