SCHEMBL365486

SCHEMBL365486

CCCCCc1cccc(-c2ccccc2)c1C#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 7/20 0.44
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 1/20 0.43
PPARA Q07869 1/20 0.43
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TLR8 Q9NR97 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
BID P55957 3/20 0.39
MCL1 Q07820 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317340 0.98 TSHR (0.44) CD274KDM4EALDH1A1MAPK1PPARA
SCHEMBL1641624 0.98 TSHR (0.44) CD274KDM4EALDH1A1MAPK1PPARA
SCHEMBL15063661 0.98 TSHR (0.44) CD274KDM4EALDH1A1MAPK1PPARA
SCHEMBL9620444 0.98 TSHR (0.44) CD274KDM4EALDH1A1MAPK1PPARA
SCHEMBL11292965 0.98 TSHR (0.44) CD274KDM4EALDH1A1MAPK1PPARA
SCHEMBL27569853 0.95 CD274 (0.44) CD274KDM4EALDH1A1MAPK1SMN1; SMN2
SCHEMBL29210714 0.89 KDM4E (0.47) CD274KDM4EALDH1A1MAPK1SMN1; SMN2
Acrylic Acid SCHEMBL28994845 0.88 THRA (0.47) KDM4EPPARAHSD17B10BIDMCL1
SCHEMBL6961873 0.86 CYP3A4 (0.47) CD274KDM4EALDH1A1PPARATSHR
SCHEMBL27730135 0.83 PPARA (0.51) CD274PPARALIPGNR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217583-A1 COMPOSITIONS OF MATERIALS FOR FABRICATION OF EVACUATED PERIODIC GRATINGS DIGILENS INC. (US) 2025-10-16 WO claimed
US-11444427-B2 Electrically tunable laser with cholesteric liquid crystal heliconical structure KENT STATE UNIVERSITY (US) 2022-09-13 US claimed
CN-114450608-A Vacuum Bragg grating and method of manufacture 迪吉伦斯公司 2022-05-06 CN claimed
US-7361288-B2 Components for high-frequency technology MERCK PATENT GESELLSCHAFT MIT BESSCHRANKTER HAFTUNG (DE) 2008-04-22 US claimed
US-20050067605-A1 Components for high-frequency technology MERCK PATENT GESELLSCHAFT (DE) 2005-03-31 US claimed
US-4639091-A Static deflector device for an infrared beam THOMSON-CSF (FR) 1987-01-27 US claimed
JP-54045684-A None JP disclosed
JP-10114894-A None JP disclosed
JP-60115684-A None JP disclosed
JP-54056085-A None JP disclosed
WO-2025217583-A1 COMPOSITIONS OF MATERIALS FOR FABRICATION OF EVACUATED PERIODIC GRATINGS DIGILENS INC. (US) 2025-10-16 WO disclosed
US-12428605-B2 Composite condensed matter material and methods of using and forming same THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2025-09-30 US disclosed
US-20250172728-A1 Evacuated Periotic Structures and Methods of Manufacturing DIGILENS INC. (US) 2025-05-29 US disclosed
US-4211473-A Liquid crystal display devices THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1980-07-08 US disclosed
EP-0012440-A1 Methods of producing liquid crystal display cells International Business Machines Corporation (US) 1980-06-25 EP disclosed
JP-S5456085-A LIQUID CRYSTAL COMPOSITION NEC CORP 1979-05-04 JP disclosed
JP-S5445684-A LIQUID CRYSTAL DISPLAY DEVICE NEC CORP 1979-04-11 JP disclosed
US-4119367-A Liquid crystal displays RAYNES EDWARD PETER 1978-10-10 US disclosed
US-4109241-A LIQUID CRYSTAL DISPLAYS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1978-08-22 US disclosed
US-4038439-A METHOD FOR PRODUCING SELECTED ALIGNMENT IN LIQUID CRYSTAL INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1977-07-26 US disclosed