Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 18/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655174 | 0.92 | NPSR1 (0.37) | ANO1EPHX1EPHX2 | |
| SCHEMBL1953497 | 0.89 | ANO1 (0.52) | ANO1ANO2 | |
| SCHEMBL1952342 | 0.85 | ANO1 (0.54) | ANO1ANO2 | |
| SCHEMBL12756765 | 0.74 | ALDH1A1 (0.41) | ANO1 | |
| SCHEMBL7957424 | 0.73 | ANO1 (0.57) | ANO1ANO2 | |
| SCHEMBL7951495 | 0.72 | PRMT5 (0.34) | ANO1 | |
| SCHEMBL1954070 | 0.70 | ANO1 (0.61) | ANO1ANO2 | |
| SCHEMBL1953124 | 0.69 | ANO1 (0.57) | ANO1ANO2 | |
| SCHEMBL1951883 | 0.69 | ANO1 (0.57) | ANO1ANO2 | |
| SCHEMBL1907652 | 0.69 | ANO1 (0.57) | ANO1ANO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |