Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14777208 | 0.83 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL21104407 | 0.83 | LOXL2 (0.49) | LOXL2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3755442 | 0.80 | LOXL2 (0.46) | LOXL2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL15689586 | 0.79 | HDAC6 (0.51) | LOXL2NPC1HDAC6EPHX2PTGER1 | |
| SCHEMBL15689757 | 0.79 | HDAC6 (0.48) | LOXL2NPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL2320663 | 0.78 | HDAC6 (0.47) | LOXL2NPC1RAB9AHDAC6EPHX2 | |
| SCHEMBL2317788 | 0.78 | HDAC6 (0.47) | LOXL2NPC1RAB9AHDAC6EPHX2 | |
| SCHEMBL3656822 | 0.78 | LOXL2 (0.47) | LOXL2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3746477 | 0.77 | LOXL2 (0.45) | LOXL2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3746479 | 0.77 | LOXL2 (0.43) | LOXL2NPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203219-A1 | SUBSTITUTED BENAMIDINES AS ANTIBACTERIAL AGENTS | Biota Europe Ltd (GB) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009040507-A1 | SUBSTITUTED BENAMIDINES AS ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2009-04-02 | — | — | WO | disclosed |