Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.42 |
| ▸ | RELA | Q04206 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777067 | 0.85 | MAPT (0.52) | RAB9ANPC1KDM4EMAPTGAA | |
| SCHEMBL3648116 | 0.83 | BCL2L1 (0.49) | RAB9ANPC1KDM4EATMMAPT | |
| SCHEMBL3012995 | 0.80 | MAPT (0.58) | RAB9ANPC1KDM4EATMMAPT | |
| SCHEMBL3013006 | 0.80 | MAPT (0.58) | RAB9ANPC1KDM4EATMMAPT | |
| SCHEMBL3651313 | 0.79 | RAB9A (0.47) | RAB9ANPC1KDM4EMAPTGAA | |
| SCHEMBL3655494 | 0.78 | RAB9A (0.44) | RAB9ANPC1KDM4EATMMAPT | |
| SCHEMBL3655217 | 0.73 | SMN1; SMN2 (0.47) | RAB9ANPC1KDM4EMAPTGAA | |
| SCHEMBL3649157 | 0.72 | GAA (0.54) | RAB9ANPC1KDM4EMAPTGAA | |
| SCHEMBL3652381 | 0.72 | MAPT (0.44) | RAB9ANPC1KDM4EMAPTGAA | |
| SCHEMBL3655308 | 0.72 | GAA (0.44) | RAB9ANPC1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193127-A1 | BENZOTHIAZOLE COMPOUNDS | The Walter and Eliza Hall Institute of Medical Research (AU) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009039553-A1 | BENZOTHIAZOLE COMPOUNDS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2009-04-02 | — | — | WO | disclosed |