Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.46 |
| ▸ | CA2 | P00918 | 16/20 | 0.46 |
| ▸ | CA9 | Q16790 | 15/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA7 | P43166 | 5/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.46 |
| ▸ | CA3 | P07451 | 4/20 | 0.46 |
| ▸ | CA4 | P22748 | 4/20 | 0.46 |
| ▸ | CA6 | P23280 | 4/20 | 0.46 |
| ▸ | CA5A | P35218 | 4/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17183005 | 1.00 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL17183011 | 1.00 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL5024582 | 0.89 | CA1 (0.39) | CA1CA2CA9CA12CA7 | |
| SCHEMBL17183004 | 0.80 | FNTA (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL3655506 | 0.80 | FNTA (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL17183010 | 0.80 | FNTA (0.46) | CA1CA2CA9CA12CA7 | |
| Potassium Ion SCHEMBL3787521 | 0.80 | RECQL (0.40) | CA1CA2CA9CA12CA7 | |
| SCHEMBL3844911 | 0.78 | RECQL (0.63) | CA1CA2CA9CA12CA7 | |
| SCHEMBL31174722 | 0.78 | RECQL (0.63) | CA1CA2CA9CA12CA7 | |
| SCHEMBL5026205 | 0.77 | PTGS1 (0.32) | CA1CA2CA9TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197494-A2 | FUNCTIONALIZED NANOPARTICLES FOR THE INHIBITION OF SELECTIN-MEDIATED CELL ADHESION | Freie Universität Berlin (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009030492-A2 | FUNCTIONALIZED NANOPARTICLES FOR THE INHIBITION OF SELECTIN-MEDIATED CELL ADHESION | FREIE UNIVERSITÄT BERLIN (DE) | 2009-03-12 | — | — | WO | disclosed |
| EP-2033660-A1 | Functionalized nanoparticles for the inhibition of selectin-mediated cell adhesion | Freie Universität Berlin (DE) | 2009-03-11 | — | — | EP | disclosed |