SCHEMBL5026205

SCHEMBL5026205

O=S(=O)(OCCS)OCCS

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.32
PDE4A P27815 1/20 0.32
KDM4E B2RXH2 2/20 0.30
ALOX15 P16050 2/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MMP9 P14780 1/20 0.30
TSHR P16473 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12601439 0.83
SCHEMBL5024582 0.81 CA1 (0.39) KDM4EALOX15USP2ALDH1A1LMNA
SCHEMBL3655503 0.77 CA1 (0.46) KDM4EALOX15USP2ALDH1A1LMNA
SCHEMBL17183005 0.77 CA1 (0.46) KDM4EALOX15USP2ALDH1A1LMNA
SCHEMBL17183011 0.77 CA1 (0.46) KDM4EALOX15USP2ALDH1A1LMNA
SCHEMBL4615228 0.75
SCHEMBL153103 0.75
SCHEMBL28046726 0.73
SCHEMBL11056239 0.73
SCHEMBL27845994 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2762485-B1 METHOD FOR PRODUCING POLYPEPTIDE FRAGMENT WITH HIGH EFFICIENCY, WHICH IS SUITABLE FOR NCL METHOD GLYTECH INC (JP) 2018-08-01 EP disclosed
EP-1379232-B1 N-ACETYLCYSTEINE COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF DRUG TOXICITY UNIV LELAND STANFORD JUNIOR (US) 2015-07-29 EP disclosed
US-20140377807-A1 METHOD FOR PRODUCING POLYPEPTIDE FRAGMENT WITH HIGH EFFICIENCY, WHICH IS SUITABLE FOR NCL METHOD GLYTECH, INC. (JP) 2014-12-25 US disclosed
CN-104080796-A Method for producing polypeptide fragment with high efficiency, which is suitable for NCL method GLYTECH INC 2014-10-01 CN disclosed
EP-2762485-A1 METHOD FOR PRODUCING POLYPEPTIDE FRAGMENT WITH HIGH EFFICIENCY, WHICH IS SUITABLE FOR NCL METHOD Glytech, Inc. (JP) 2014-08-06 EP disclosed
US-7442459-B2 Solid electrolyte, membrane and electrode assembly, and fuel cell FUJIFILM CORPORATION (JP) 2008-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140377807-A1 METHOD FOR PRODUCING POLYPEPTIDE FRAGMENT WITH HIGH EFFICIENCY, WHICH IS SUITABLE FOR NCL METHOD MET, NCLN, LNPEP PTGS1 4808/4885PDE4A 4847/4885KDM4E 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.