Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 6/20 | 0.47 |
| ▸ | ITPR2 | Q14571 | 2/20 | 0.45 |
| ▸ | ITPR1 | Q14643 | 2/20 | 0.45 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651791 | 1.00 | ITPR3 (0.47) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL3656282 | 1.00 | ITPR3 (0.47) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL4191662 | 0.87 | SMPD1 (0.50) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL7798872 | 0.87 | SMPD1 (0.50) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL4442196 | 0.87 | SMPD1 (0.50) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL8859419 | 0.85 | ITPR3 (0.52) | ITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL30412792 | 0.85 | ITPR3 (0.52) | ITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL4596697 | 0.85 | SMPD1 (0.48) | ITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL4595256 | 0.85 | SMPD1 (0.48) | ITPR3ITPR2ITPR1SMPD1 | |
| SCHEMBL5378658 | 0.85 | SMPD1 (0.48) | ITPR3ITPR2ITPR1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2187892-A1 | METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA | Bioneris AB (SE) | 2010-05-26 | — | — | EP | claimed |
| WO-2009038533-A1 | METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA | BIONERIS AB (SE) | 2009-03-26 | — | — | WO | claimed |