Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17913073 | 0.79 | — | — | |
| SCHEMBL17913074 | 0.79 | — | — | |
| SCHEMBL4998358 | 0.78 | — | — | |
| Hydrogen Peroxide SCHEMBL65467 | 0.69 | TRPA1 (0.41) | ROCK2ROCK1TRPA1TRPM8EPHX1 | |
| SCHEMBL1760669 | 0.68 | TRPA1 (0.39) | TRPA1TRPM8EPHX1 | |
| SCHEMBL452781 | 0.68 | TRPA1 (0.39) | TRPA1TRPM8EPHX1 | |
| SCHEMBL7979 | 0.68 | TRPA1 (0.39) | TRPA1TRPM8EPHX1 | |
| Bicarbonate SCHEMBL10767839 | 0.68 | EPHX1 (0.39) | ROCK2ROCK1TRPA1TRPM8TRPV1 | |
| Phenol SCHEMBL5475642 | 0.67 | ESR2 (0.46) | ROCK2ROCK1TRPM8 | |
| Charcoal, Activated SCHEMBL4530459 | 0.66 | TRPA1 (0.37) | TRPA1TRPM8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916307-B1 | Plant enzymes for bioconversion | DAFRA PHARMA RES & DEV BVBA (BE) | 2014-02-26 | — | — | EP | disclosed |
| US-8163980-B2 | Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-24 | — | — | US | disclosed |
| US-8097438-B2 | Nucleic acids encoding modified cytochrome P450 enzymes and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-17 | — | — | US | disclosed |
| WO-2011121456-A2 | NUCLEIC ACIDS AND PROTEIN SEQUENCES OF COSTUNOLIDE SYNTHASE | UTI LIMITED PARTNERSHIP (CA) | 2011-10-06 | — | — | WO | disclosed |
| US-20110008829-A1 | Use of Synthetic Scaffolds for the Production of Biosynthetic Pathway Products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-01-13 | — | — | US | disclosed |
| US-20080124772-A1 | Plant enzymes for bioconversion | PLANT RESEARCH INTERNATIONAL B.V. | 2008-05-29 | — | — | US | disclosed |
| EP-1916307-A1 | Plant enzymes for bioconversion | Plant Research International B.V. (NL) | 2008-04-30 | — | — | EP | disclosed |
| US-20070300327-A1 | Plant enzymes for bioconversion | PLANT RESEARCH INTERNATIONAL B.V. | 2007-12-27 | — | — | US | disclosed |
| US-7214507-B2 | Plant enzymes for bioconversion | PLANT RESEARCH INTERNATIONAL B.V. (NL) | 2007-05-08 | — | — | US | disclosed |
| US-20050019882-A1 | Using plant enzymes for the production of flavor, fragrance, pharmaceutical or bio-control agents from less valuable substrates; terpenoid biosynthesis | STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) | 2005-01-27 | — | — | US | disclosed |
| EP-1427838-A1 | PLANT ENZYMES FOR BIOCONVERSION | Plant Research International B.V. (NL) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003025193-A1 | PLANT ENZYMES FOR BIOCONVERSION | PLANT RESEARCH INTERNATIONAL B.V. (NL) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124772-A1 | Plant enzymes for bioconversion | STS, SQLE, CYP51A1 | ROCK2 2628/4885ROCK1 2804/4885TRPA1 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.