Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257241 | 1.00 | HDAC1 (0.52) | HDAC1MEN1KMT2ALMNAITGB1 | |
| SCHEMBL8258871 | 0.90 | HDAC1 (0.58) | HDAC1MEN1KMT2ALMNACAPN1 | |
| SCHEMBL8258865 | 0.89 | HDAC1 (0.56) | HDAC1MEN1KMT2ALMNACAPN1 | |
| SCHEMBL5809254 | 0.89 | HDAC1 (0.56) | HDAC1MEN1KMT2ALMNACAPN1 | |
| SCHEMBL5805403 | 0.83 | KMT2A (0.57) | HDAC1MEN1KMT2ALMNACAPN1 | |
| SCHEMBL5809231 | 0.81 | HDAC1 (0.67) | HDAC1 | |
| SCHEMBL8259001 | 0.81 | HDAC1 (0.67) | HDAC1 | |
| SCHEMBL8260313 | 0.80 | HDAC1 (0.56) | HDAC1 | |
| SCHEMBL5818156 | 0.80 | HDAC1 (0.61) | HDAC1 | |
| SCHEMBL8258575 | 0.80 | HDAC1 (0.53) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195029-A2 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | Oryzon Genomics SA (ES) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009027349-A2 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS SA (ES) | 2009-03-05 | — | — | WO | disclosed |