Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.56 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258865 | 1.00 | HDAC1 (0.56) | HDAC1USP30MEN1KMT2ALMNA | |
| SCHEMBL8258871 | 0.96 | HDAC1 (0.58) | HDAC1USP30MEN1KMT2ALMNA | |
| SCHEMBL3655932 | 0.89 | HDAC1 (0.52) | HDAC1USP30MEN1KMT2ALMNA | |
| SCHEMBL8257241 | 0.89 | HDAC1 (0.52) | HDAC1USP30MEN1KMT2ALMNA | |
| SCHEMBL5805403 | 0.89 | KMT2A (0.57) | HDAC1USP30MEN1KMT2ALMNA | |
| SCHEMBL8260313 | 0.88 | HDAC1 (0.56) | HDAC1 | |
| SCHEMBL5806240 | 0.87 | HDAC1 (0.53) | HDAC1 | |
| SCHEMBL8258575 | 0.87 | HDAC1 (0.53) | HDAC1 | |
| SCHEMBL5808207 | 0.86 | HDAC1 (0.55) | HDAC1USP30 | |
| SCHEMBL8258867 | 0.86 | HDAC1 (0.55) | HDAC1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | claimed |