Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RARA | P10276 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328524 | 0.95 | RARB (0.66) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL10866701 | 0.90 | RARB (0.63) | RARBALDH1A1MEN1RARAMAPT | |
| Terephthalic Acid SCHEMBL5179959 | 0.89 | RARB (0.57) | RARBALDH1A1KMT2ATP53TSHR | |
| SCHEMBL9260821 | 0.88 | RARB (0.64) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL986621 | 0.87 | ALDH1A1 (0.57) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL14672531 | 0.87 | RARB (0.65) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL9252748 | 0.87 | RARB (0.62) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL8775067 | 0.87 | RARB (0.65) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL27934597 | 0.84 | ALDH1A1 (0.48) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL1749934 | 0.84 | ALDH1A1 (0.57) | RARBALDH1A1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |