SCHEMBL3657161

SCHEMBL3657161

O=C(NC(=O)c1ccccc1Cl)Nc1nc2ccc(S(=O)(=O)CCNCCc3ccccc3)cc2s1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1786216 0.91 GHSR (0.77) GHSR
SCHEMBL1785900 0.90 GHSR (0.76) GHSR
SCHEMBL1784587 0.89 GHSR (0.92) GHSR
SCHEMBL1786469 0.87 GHSR (0.82) GHSR
SCHEMBL1785403 0.87 GHSR (0.74) GHSR
SCHEMBL1786725 0.87 GHSR (0.82) GHSR
SCHEMBL1785627 0.87 GHSR (0.83) GHSR
SCHEMBL1786915 0.86 GHSR (0.80) GHSR
SCHEMBL1785989 0.86 GHSR (0.82) GHSR
SCHEMBL1786346 0.86 GHSR (0.82) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2205576-A1 BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS AstraZeneca AB (SE) 2010-07-14 EP claimed
WO-2009047558-A1 BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS ASTRAZENECA AB (SE) 2009-04-16 WO claimed
EP-2205576-A1 BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS AstraZeneca AB (SE) 2010-07-14 EP disclosed
WO-2009047558-A1 BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS ASTRAZENECA AB (SE) 2009-04-16 WO disclosed