Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647167 | 0.82 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| SCHEMBL3788234 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| SCHEMBL31607654 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| SCHEMBL29900994 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL28890403 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| SCHEMBL1357302 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| SCHEMBL3785264 | 0.76 | POLB (0.71) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| SCHEMBL31607661 | 0.76 | POLB (0.71) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| SCHEMBL397259 | 0.75 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 | |
| SCHEMBL31607639 | 0.72 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CYP3A4TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593226-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | Abbvie Inc. (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012009698-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |