Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659395 | 0.91 | P2RX3 (0.54) | P2RX3P2RX2 | |
| SCHEMBL3660215 | 0.85 | P2RX3 (0.59) | P2RX3P2RX2 | |
| SCHEMBL4417922 | 0.84 | P2RX3 (0.73) | P2RX3P2RX2 | |
| SCHEMBL3655316 | 0.83 | P2RX3 (0.51) | P2RX3P2RX2 | |
| SCHEMBL16875763 | 0.80 | P2RX3 (0.43) | P2RX3P2RX2 | |
| SCHEMBL639691 | 0.79 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL3781695 | 0.79 | P2RX3 (0.64) | P2RX3P2RX2 | |
| SCHEMBL639717 | 0.78 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL3662324 | 0.78 | P2RX3 (0.65) | P2RX3P2RX2 | |
| SCHEMBL2275053 | 0.77 | P2RX3 (0.64) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234989-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDE DERIVATIVES AND THEIR USE AS P2X3 AND/OR P2X2/3 PURINERGIC RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009077371-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDE DERIVATIVES AND THEIR USE AS P2X3 AND/OR P2X2/3 PURINERGIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-06-25 | — | — | WO | disclosed |
| EP-2038264-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008000645-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | disclosed |