Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 17/20 | 0.55 |
| ▸ | PGR | P06401 | 13/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988168 | 0.81 | NR3C1 (0.41) | NR3C1NR3C2PGR | |
| SCHEMBL3652176 | 0.77 | NR3C1 (0.39) | NR3C1NR3C2PGR | |
| SCHEMBL6226560 | 0.77 | NR3C1 (0.50) | NR3C1NR3C2PGR | |
| SCHEMBL3651469 | 0.75 | NR3C1 (0.39) | NR3C1NR3C2PGR | |
| SCHEMBL3658140 | 0.74 | NR3C1 (0.60) | NR3C1NR3C2PGR | |
| SCHEMBL4437967 | 0.73 | NR3C1 (0.38) | NR3C1NR3C2PGR | |
| SCHEMBL293763 | 0.72 | NR3C1 (0.77) | NR3C1NR3C2PGR | |
| SCHEMBL6230117 | 0.72 | NR3C1 (0.38) | NR3C1NR3C2PGR | |
| SCHEMBL1634236 | 0.71 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL1633520 | 0.70 | NR3C1 (0.85) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203160-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | Bausch & Lomb Incorporated (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009042377-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | BAUSCH & LOMB INCORPORATED (US) | 2009-04-02 | — | — | WO | disclosed |