Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glyceryl Monostearate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.88 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.88 |
| ▸ | MEN1 | O00255 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.88 |
| ▸ | DGKA | P23743 | 1/20 | 0.74 |
| ▸ | FAAH | O00519 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PRKCA | P17252 | 3/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.58 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.58 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.58 |
| ▸ | PAM | P19021 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Behenic Acid SCHEMBL190890 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Monoctanoin Component B SCHEMBL8394660 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Decanoic Acid SCHEMBL4663166 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Glycerol Monolaurate SCHEMBL2241699 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Palmitic Acid SCHEMBL23850779 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL1960888 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Monoctanoin Component A SCHEMBL25311832 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Nonadecanoic Acid SCHEMBL2028549 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Heptadecanoic Acid SCHEMBL2006352 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Glyceryl Monostearate SCHEMBL16684813 | 1.00 | LMNA (0.88) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024144823-A1 | FORMULATIONS AND METHODS FOR SKIN CARE OR HYALURONIC ACID SYNTHESIS | Entrinsic, LLC (US) | 2024-07-04 | — | — | WO | claimed |
| CN-118058980-B | Biphase mud film and preparation method thereof | 广州百孚润化工有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118058980-A | Biphase mud film and preparation method thereof | 广州百孚润化工有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118001205-A | Anti-wrinkle active composition and application thereof, and anti-wrinkle cream | 威莱(广州)日用品有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2023130094-A2 | FORMULATIONS AND METHODS FOR SKIN CARE | Entrinsic, LLC (US) | 2023-07-06 | — | — | WO | claimed |
| US-11331254-B2 | Compositions for providing a protective barrier | L'OREAL (FR) | 2022-05-17 | — | — | US | claimed |
| CN-114129462-A | Low viscosity water-in-oil-in-water multiple emulsion cosmetic compositions | 科丝美诗株式会社 | 2022-03-04 | — | — | CN | claimed |
| CN-112675101-A | Whitening and freckle-removing composition, whitening and freckle-removing cream and preparation method thereof | 上海柔素生物科技有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-112336672-A | Fermentation method of bletilla striata fermentation product and application of bletilla striata fermentation product in whitening cosmetics | 中华全国供销合作总社南京野生植物综合利用研究所 | 2021-02-09 | — | — | CN | claimed |
| CN-107440947-B | Composition with moisturizing effect, application thereof, moisturizing cream and preparation method thereof | 广州堂本生物科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-105188652-A | Cosmetic or dermatological emulsion comprising a merocyanine and an emulsifying system containing an alkali metal salt of a fatty alcohol phosphate | OREAL S A | 2015-12-23 | — | — | CN | claimed |
| EP-2945607-A1 | COSMETIC OR DERMATOLOGICAL EMULSION COMPRISING A MEROCYANINE AND AN EMULSIFYING SYSTEM CONTAINING AN ALKALI METAL SALT OF A PHOSPHORIC ACID ESTER OF A FATTY ALCOHOL | L'Oréal (FR) | 2015-11-25 | — | — | EP | claimed |
| CN-104887896-A | Massage cream and traditional Chinese medicine composition for cyclomastopathy treatment and preparation method of massage cream and traditional Chinese medicine composition for cyclomastopathy treatment | SYNSUN HEALTH INDUSTRY CO LTD | 2015-09-09 | — | — | CN | claimed |
| US-20140271596-A1 | EMULSIFIED HYDROGEL COMPOSITION AND A PRODUCTION METHOD THEREFOR | GENIC CO., LTD. (KR) | 2014-09-18 | — | — | US | claimed |
| CN-104042511-A | Muddy facial mask containing natural volcanic mineral mud powder | NOX BELLCOW ZS NONWOVEN CHEMICAL LTD | 2014-09-17 | — | — | CN | claimed |
| EP-2772270-A1 | EMULSIFIED HYDROGEL COMPOSITION AND A PRODUCTION METHOD THEREFOR | Genic Co., Ltd. (KR) | 2014-09-03 | — | — | EP | claimed |
| WO-2014111562-A1 | COSMETIC OR DERMATOLOGICAL EMULSION COMPRISING A MEROCYANINE AND AN EMULSIFYING SYSTEM CONTAINING AN ALKALI METAL SALT OF A PHOSPHORIC ACID ESTER OF A FATTY ALCOHOL | L'OREAL (FR) | 2014-07-24 | — | — | WO | claimed |
| CN-101157557-A | Molybdenum disilicide silicon aluminum oxygen nitrogen material composite heater and preparation method thereof | UNIV CENTRAL SOUTH (CN) | 2008-04-09 | — | — | CN | claimed |
| CN-1771969-A | Externally applied emulsion for treating dermatitis and eczema | BOYUAN BIOMEDICINE CO LTD XI A (CN) | 2006-05-17 | — | — | CN | claimed |
| CN-85108076-A | The prescription and the production technology of \" skin that health \" exterior-applied emulsion | — | 1986-09-03 | — | — | CN | claimed |