Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL28536336 | 0.87 | TSHR (0.59) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL271385 | 0.84 | L3MBTL1 (0.52) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL34953 | 0.84 | TSHR (0.70) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| Methyl Benzoate SCHEMBL28106657 | 0.83 | TSHR (0.83) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL29966404 | 0.82 | TSHR (0.67) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL8054504 | 0.82 | TSHR (0.67) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| Methyl Alcohol SCHEMBL28469619 | 0.82 | TSHR (0.67) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| Potassium SCHEMBL30190417 | 0.82 | TSHR (0.67) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| Ammonia Solution, Strong SCHEMBL28556515 | 0.82 | TSHR (0.67) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL10941453 | 0.82 | TSHR (0.67) | TSHRRAB9ALOXL2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220042-A1 | NOVEL BIFUNCTIONAL COMPOUNDS WHICH INHIBIT PROTEIN KINASES AND HISTONE DEACETYLASES | 4SC AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063054-A1 | NOVEL BIFUNCTIONAL COMPOUNDS WHICH INHIBIT PROTEIN KINASES AND HISTONE DEACETYLASES | 4SC AG (DE) | 2009-05-22 | — | — | WO | disclosed |
| US-5176989-A | Control of light and dark fading | FUJI PHOTO FILM CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0256531-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | Fuji Photo Film Co., Ltd. (JP) | 1992-11-25 | — | — | EP | disclosed |
| US-4946770-A | CYAN DYE IMAGES EXCELLENT IN PRESERAVIBILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0256531-A2 | Silver halide color photographic material | Fuji Photo Film Co., Ltd. (JP) | 1988-02-24 | — | — | EP | disclosed |