Sugi Predict

Sugi Predict / Compounds / Lanosterol

Lanosterol

Lanosterol

SCHEMBL3658283

CC(C)=CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3.CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CRYAB P02511 4/20 0.89
▸ MAPT P10636 3/20 0.89
▸ USP2 O75604 2/20 0.89
▸ ALDH1A1 P00352 2/20 0.89
▸ CYP3A4 P08684 2/20 0.89
▸ ALOX15 P16050 2/20 0.89
▸ LMNA P02545 1/20 0.89
▸ PTGES O14684 3/20 0.71
▸ CRYAA P02489 1/20 0.69
▸ FNTA P49354 1/20 0.67
▸ FNTB P49356 1/20 0.67
▸ ACHE P22303 1/20 0.57
▸ MEN1 O00255 1/20 0.56
▸ PLA2G1B P04054 1/20 0.56
▸ DNMT1 P26358 1/20 0.56
▸ BLM P54132 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ ATG4B Q9Y4P1 1/20 0.56
▸ HMGCR P04035 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lanosterol SCHEMBL14240642 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL14536063 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL19194030 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL145835 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL2154745 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL14360758 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL145834 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL1696473 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL21348006 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4
Lanosterol SCHEMBL16994483 0.94 MAPT (1.00) CRYABMAPTUSP2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2219587-A1 STEROL-MODIFIED AMPHIPHILIC LIPIDS The Regents of the University of California (US) 2010-08-25 — — EP disclosed
WO-2009064696-A1 STEROL-MODIFIED AMPHIPHILIC LIPIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-05-22 — — WO disclosed