Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.54 |
| ▸ | CNR1 | P21554 | 11/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658651 | 0.87 | CNR2 (0.58) | CNR2CNR1POLBGAANPY5R | |
| SCHEMBL3783928 | 0.84 | POLB (0.47) | CNR2CNR1POLBGAANPY5R | |
| SCHEMBL3661265 | 0.81 | CNR2 (0.52) | CNR2CNR1POLBGAAEGFR | |
| SCHEMBL3660664 | 0.77 | CNR1 (0.56) | CNR2CNR1POLBGAAEGFR | |
| SCHEMBL3654312 | 0.75 | NPY5R (0.47) | CNR2CNR1POLBGAANPY5R | |
| SCHEMBL4172018 | 0.74 | CNR2 (0.68) | CNR2CNR1GAANPY5RCYP2C8 | |
| SCHEMBL3783922 | 0.74 | POLB (0.47) | CNR2CNR1POLBGAANPY5R | |
| SCHEMBL3656884 | 0.72 | NPY5R (0.51) | CNR2CNR1POLBGAANPY5R | |
| SCHEMBL3654121 | 0.72 | CNR1 (0.54) | CNR2CNR1POLBGAAEGFR | |
| SCHEMBL1464269 | 0.71 | CNR2 (1.00) | CNR2CNR1GAACYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217565-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2010-08-18 | — | — | EP | claimed |
| WO-2009061652-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-14 | — | — | WO | claimed |