Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 5/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 5/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
| ▸ | GCG | P01275 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114225 | 0.92 | DDR1 (0.38) | KCNK2KCNK10DDR1GCGRGCG | |
| SCHEMBL3113811 | 0.92 | KCNK2 (0.40) | KCNK2KCNK10DDR1GCGRGCG | |
| SCHEMBL3115945 | 0.91 | KCNK2 (0.39) | KCNK2KCNK10DDR1GCGRGCG | |
| SCHEMBL3102189 | 0.91 | KCNK2 (0.39) | KCNK2KCNK10GCGRGCGEPHX2 | |
| SCHEMBL3110314 | 0.90 | DDR1 (0.38) | KCNK2KCNK10DDR1GCGRGCG | |
| SCHEMBL3111589 | 0.90 | ROCK2 (0.36) | KCNK2KCNK10DDR1GCGRGCG | |
| SCHEMBL3102247 | 0.90 | CNR1 (0.39) | KCNK2KCNK10DDR1GCGRGCG | |
| SCHEMBL3103535 | 0.89 | KCNK2 (0.39) | KCNK2KCNK10DDR1EPHX2NR1H4 | |
| SCHEMBL3116597 | 0.89 | KCNK2 (0.40) | KCNK2KCNK10DDR1GCGRGCG | |
| SCHEMBL3106166 | 0.88 | DDR1 (0.36) | KCNK2KCNK10DDR1GCGRGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209768-A1 | 5,6-DIARYL PYRIDINES SUBSTITUTED IN THE 2- AND 3-POSITION, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009087285-A1 | 5,6-DIARYL PYRIDINES SUBSTITUTED IN THE 2- AND 3-POSITION, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-07-16 | — | — | WO | disclosed |