SCHEMBL3658849

SCHEMBL3658849

Cc1ccc(CNC(=O)Cc2cccc(CC(C)(C)NCC(O)c3ccc(O)c(NC=O)c3)c2)cc1C

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 20/20 0.66
CHRM3 P20309 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3624830 1.00 ADRB2 (0.66) ADRB2CHRM3
SCHEMBL3624828 1.00 ADRB2 (0.66) ADRB2CHRM3
SCHEMBL3619543 0.91 ADRB2 (0.79) ADRB2CHRM3
SCHEMBL3619539 0.91 ADRB2 (0.79) ADRB2CHRM3
SCHEMBL5034417 0.89 ADRB2 (0.83) ADRB2CHRM3
SCHEMBL3623819 0.89 ADRB2 (0.80) ADRB2CHRM3
SCHEMBL3623815 0.89 ADRB2 (0.80) ADRB2CHRM3
SCHEMBL5034423 0.89 ADRB2 (0.83) ADRB2CHRM3
SCHEMBL3626049 0.88 ADRB2 (0.67) ADRB2CHRM3
SCHEMBL3623597 0.88 ADRB2 (0.67) ADRB2CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730103-B1 FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR PFIZER LTD (GB) 2010-05-26 EP disclosed