Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630490 | 0.98 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL3662191 | 0.89 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL592123 | 0.85 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL592122 | 0.85 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL591577 | 0.83 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL591576 | 0.83 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3628040 | 0.82 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL3427997 | 0.82 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL1837993 | 0.81 | ALDH1A1 (0.32) | — | |
| SCHEMBL3425357 | 0.80 | KCNH2 (0.33) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146987-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-27 | — | — | EP | claimed |
| WO-2008126024-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | claimed |