SCHEMBL3659367

C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc([C@](O)(C(N)=O)C(F)(F)F)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	HSD11B1	P28845	20/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3628001	1.00	HSD11B1 (1.00)	HSD11B1
SCHEMBL3621210	1.00	HSD11B1 (1.00)	HSD11B1
SCHEMBL29874192	1.00	HSD11B1 (1.00)	HSD11B1
SCHEMBL3628888	1.00	HSD11B1 (1.00)	HSD11B1
SCHEMBL3630508	0.92	HSD11B1 (0.86)	HSD11B1
SCHEMBL3216102	0.92	HSD11B1 (0.86)	HSD11B1
SCHEMBL3788502	0.92	HSD11B1 (0.84)	HSD11B1
SCHEMBL13039869	0.92	HSD11B1 (0.84)	HSD11B1
SCHEMBL3628952	0.92	HSD11B1 (0.84)	HSD11B1
SCHEMBL3622763	0.91	HSD11B1 (0.83)	HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010141550-A2	11-BETA HSD1 INHIBITORS	WYETH LLC (US)	2010-12-09	—	—	WO	claimed
WO-2010141550-A2	11-BETA HSD1 INHIBITORS	WYETH LLC (US)	2010-12-09	—	—	WO	disclosed