Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 13/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CCND1 | P24385 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003954 | 0.90 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL7951597 | 0.84 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL5970702 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL28004430 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL19852195 | 0.80 | DRD3 (0.56) | DRD2DRD4DRD3 | |
| SCHEMBL20148244 | 0.80 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL25365620 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL11784633 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL11183187 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL4702671 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205559-A1 | RENIN INHIBITORS | Cadila Healthcare Limited (IN) | 2010-07-14 | — | — | EP | claimed |
| WO-2009087649-A1 | RENIN INHIBITORS | CADILA HEALTHCARE LIMITED (IN) | 2009-07-16 | — | — | WO | claimed |