Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6115422 | 0.94 | NPY2R (0.76) | NPY2R | |
| SCHEMBL6115352 | 0.92 | NPY2R (0.81) | NPY2R | |
| SCHEMBL6115312 | 0.92 | NPY2R (0.75) | NPY2R | |
| SCHEMBL6114950 | 0.92 | NPY2R (1.00) | NPY2R | |
| SCHEMBL5081483 | 0.91 | NPY2R (0.76) | NPY2R | |
| SCHEMBL6115478 | 0.90 | NPY2R (0.72) | NPY2R | |
| SCHEMBL6115799 | 0.90 | NPY2R (0.84) | NPY2R | |
| SCHEMBL5083798 | 0.89 | NPY2R (0.74) | NPY2R | |
| SCHEMBL6115573 | 0.89 | NPY2R (0.83) | NPY2R | |
| SCHEMBL4553605 | 0.88 | NPY2R (1.00) | NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101827595-B | Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor | NOVARTIS AG | 2013-07-24 | — | — | CN | claimed |
| CN-101827595-B | Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor | NOVARTIS AG | 2013-07-24 | — | — | CN | disclosed |
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-24 | — | — | US | disclosed |
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-24 | — | — | US | disclosed |
| CN-101827595-A | Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor | NOVARTIS AG | 2010-09-08 | — | — | CN | disclosed |
| EP-2205561-A2 | SUBSTITUTED PIPERAZINES AND PIPERIDINES AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | Novartis Ag (CH) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009079597-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009079597-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009050197-A2 | SUBSTITUTED PIPERAZINES AND PIPERIDINES AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | NOVARTIS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050197-A2 | SUBSTITUTED PIPERAZINES AND PIPERIDINES AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | NOVARTIS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| US-20090099199-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | disclosed |
| US-20090099199-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | disclosed |
| US-20090099199-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | NPY2R, NPY1R, NPY5R | NPY2R 1/4885 |
| US-20090099199-A1 | ORGANIC COMPOUNDS | SLCO4C1, SLC10A6, SLCO1B1 | NPY2R 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.