Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662076 | 0.91 | KMT2A (0.55) | KMT2AMEN1USP2CRHBPCRHR2 | |
| SCHEMBL3659938 | 0.90 | KMT2A (0.61) | KMT2AMEN1USP2CRHBPCRHR2 | |
| SCHEMBL3660498 | 0.90 | KMT2A (0.61) | KMT2AMEN1USP2CRHBPCRHR2 | |
| SCHEMBL3713752 | 0.90 | FPR2 (0.57) | KMT2AMEN1USP2CRHBPCRHR2 | |
| SCHEMBL3663169 | 0.90 | TSHR (0.59) | KMT2AMEN1USP2CRHBPCRHR2 | |
| SCHEMBL3655610 | 0.87 | MEN1 (0.65) | KMT2AMEN1POLB | |
| SCHEMBL28788580 | 0.86 | KMT2A (0.49) | KMT2AMEN1USP2CRHBPCRHR2 | |
| SCHEMBL3663220 | 0.83 | CYP2C19 (0.56) | KMT2AMEN1USP2POLBPKM | |
| SCHEMBL12318021 | 0.83 | CYP2C19 (0.60) | KMT2AMEN1USP2CYP2C19 | |
| SCHEMBL3663218 | 0.83 | CYP2C19 (0.56) | KMT2AMEN1USP2POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101827840-A | Imidazolidine-2,4-dione (hydantoin) derivatives useful as npy y2 receptor modulators | NOVARTIS AG | 2010-09-08 | — | — | CN | claimed |
| EP-2212314-A1 | IMIDAZOLIDINE-2,4-DIONE (HYDANTOIN) DERIVATIVES USEFUL AS NPY Y2 RECEPTOR MODULATORS | Novartis AG (CH) | 2010-08-04 | — | — | EP | claimed |
| WO-2009050200-A1 | IMIDAZOLIDINE-2,4-DIONE (HYDANTOIN) DERIVATIVES USEFUL AS NPY Y2 RECEPTOR MODULATORS | NOVARTIS AG (CH) | 2009-04-23 | — | — | WO | claimed |
| US-20090099243-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | claimed |
| CN-101827840-A | Imidazolidine-2,4-dione (hydantoin) derivatives useful as npy y2 receptor modulators | NOVARTIS AG | 2010-09-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099243-A1 | ORGANIC COMPOUNDS | SLCO4C1, SLCO1B1, SLCO1B3 | KMT2A 2020/4885MEN1 155/4885USP2 4800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.