Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404318 | 0.98 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL989596 | 0.98 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA12CA1CA2 | |
| Phosphine SCHEMBL22446073 | 0.96 | ALDH1A1 (0.52) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL5597248 | 0.96 | ALDH1A1 (0.52) | ALDH1A1ALOX15CA12CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL31339444 | 0.96 | ALDH1A1 (0.52) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL31553567 | 0.96 | ALDH1A1 (0.52) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL7564286 | 0.94 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL31003867 | 0.90 | ALDH1A1 (0.46) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL7260802 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL1524729 | 0.85 | CYP3A4 (0.46) | ALDH1A1ALOX15CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048731-B1 | Resin composition for fuel cell separator and fuel cell separator manufactured therefrom | NICHIAS CORP (JP) | 2010-08-25 | — | — | EP | disclosed |
| US-20090098447-A1 | RESIN COMPOSITION FOR FUEL CELL SEPARATOR, AND FUEL CELL SEPARATOR | NICHIAS CORPORATION (JP) | 2009-04-16 | — | — | US | disclosed |
| EP-2048731-A1 | Resin composition for fuel cell separator and fuel cell separator manufactured therefrom | Nichias Corporation (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1890352-A1 | Fuel cell separator composition, fuel cell separator, and method for producing the same | NICHIAS CORPORATION (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-20080032176-A1 | Fuel cell separator composition, fuel cell separator, and method for producing the same | NICHIAS CORPORATION (JP) | 2008-02-07 | — | — | US | disclosed |
| US-20060204819-A1 | Conductive epoxy resin composition and separator for fuel cell | NICHIAS CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1701400-A1 | Conductive epoxy resin composition and separator for fuel cell | NICHIAS CORPORATION (JP) | 2006-09-13 | — | — | EP | disclosed |