SCHEMBL3660935

SCHEMBL3660935

c1cnc2c(c1)oc1ccc(-n3c4ccccc4c4cc(-n5c6ccccc6c6ccccc65)ccc43)cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
NPC1 O15118 3/20 0.38
KDM4E B2RXH2 5/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 5/20 0.35
NCOA1 Q15788 1/20 0.34
PDE4D Q08499 3/20 0.34
LMNA P02545 3/20 0.33
TSHR P16473 3/20 0.33
CHRNA7 P36544 1/20 0.33
KCNH2 Q12809 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10451251 1.00 MAPT (0.38) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL13772546 0.97 MAPT (0.40) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL18381864 0.96 MAPT (0.39) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL15317417 0.95 MAPT (0.35) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL15317221 0.95 MAPT (0.35) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL16305027 0.93 CA9 (0.36) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL15317212 0.93 MAPT (0.39) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL15317165 0.93 MAPT (0.39) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL17264908 0.92 MAPT (0.36) MAPTNPC1KDM4EL3MBTL1ATM
SCHEMBL16606294 0.92 MAPT (0.36) MAPTNPC1KDM4EL3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2240446-B2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2018-09-19 EP disclosed
EP-2240446-B1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2015-11-11 EP disclosed
EP-2240446-B1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2015-11-11 EP disclosed
US-8221905-B2 Carbazole-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-07-17 US disclosed
US-8221905-B2 Carbazole-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-07-17 US disclosed
EP-2240446-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-10-20 EP disclosed
WO-2009086028-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
WO-2009086028-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES OXA1L, PAICS, ORC3 MAPT 1009/4885NPC1 2962/4885KDM4E 3635/4885
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES PAICS, CYBA, OXA1L MAPT 472/4885NPC1 3252/4885KDM4E 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.