SCHEMBL15317221

SCHEMBL15317221

c1cnc2c(c1)oc1ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6oc7cccnc7c6c5)ccc43)cc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
NPC1 O15118 2/20 0.35
NPY5R Q15761 2/20 0.34
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
PDE4D Q08499 2/20 0.32
GRM4 Q14833 1/20 0.32
NCOA1 Q15788 1/20 0.32
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15317417 1.00 MAPT (0.35) MAPTNPC1NPY5RCASP3SENP7
SCHEMBL15317165 0.98 MAPT (0.39) MAPTNPC1NPY5RCASP3SENP7
SCHEMBL15317212 0.98 MAPT (0.39) MAPTNPC1NPY5RCASP3SENP7
SCHEMBL15317170 0.97 KDM4E (0.40) MAPTNPC1NPY5RCASP3SENP7
SCHEMBL16482064 0.96 MAPT (0.39) MAPTNPC1CASP3SENP7SENP6
SCHEMBL15317163 0.96 KDM4E (0.39) MAPTNPC1NPY5RCASP3SENP7
SCHEMBL15317232 0.96 KDM4E (0.39) MAPTNPC1NPY5RCASP3SENP7
SCHEMBL15317418 0.95 MAPT (0.40) MAPTNPC1CASP3SENP7SENP6
SCHEMBL10451251 0.95 MAPT (0.38) MAPTNPC1KDM4EMEN1KMT2A
SCHEMBL3660935 0.95 MAPT (0.38) MAPTNPC1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9923151-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
US-9923151-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
US-20160118594-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20160118594-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 US disclosed
US-20150034927-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-02-05 US disclosed
US-20150034927-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-02-05 US disclosed
WO-2014057684-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 出光興産株式会社 (JP) 2014-04-17 WO disclosed
US-20130270540-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-10-17 US disclosed
US-20130270540-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME YBX1, ATXN2L, ATXN2 MAPT 2497/4885NPC1 4245/4885NPY5R 371/4885
US-20160118594-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME L1CAM, DNMT1, DNMT3L MAPT 2971/4885NPC1 4475/4885NPY5R 4066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.