Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660940 | 1.00 | CCR5 (0.65) | CCR5KCNH2 | |
| SCHEMBL4485790 | 0.89 | CCR5 (0.61) | CCR5KCNH2 | |
| SCHEMBL3631804 | 0.86 | CCR5 (0.89) | CCR5KCNH2 | |
| SCHEMBL4488251 | 0.86 | CCR5 (0.89) | CCR5KCNH2 | |
| SCHEMBL4481263 | 0.84 | CCR5 (0.56) | CCR5KCNH2 | |
| SCHEMBL4481260 | 0.84 | CCR5 (0.56) | CCR5KCNH2 | |
| SCHEMBL4481257 | 0.84 | CCR5 (0.56) | CCR5KCNH2 | |
| SCHEMBL18841093 | 0.79 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL4461717 | 0.79 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL4485795 | 0.79 | CCR5 (0.50) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142555-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. Hoffmann-Roche AG (CH) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008119663-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-10-09 | — | — | WO | disclosed |