⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27386848 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL29443934 | 0.98 | — | — | |
| SCHEMBL9164960 | 0.83 | CYP1A2 (0.41) | — | |
| SCHEMBL5845803 | 0.75 | — | — | |
| SCHEMBL30968750 | 0.75 | — | — | |
| SCHEMBL27712 | 0.75 | — | — | |
| SCHEMBL2643257 | 0.75 | — | — | |
| SCHEMBL544078 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL27899668 | 0.73 | — | — | |
| SCHEMBL30704140 | 0.73 | CYP11B2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49481-E1 | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | claimed |
| CN-115557900-A | Synthetic method of 3-substituted pyridazine derivative | 常州大学 | 2023-01-03 | — | — | CN | claimed |
| CN-111606908-B | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-109923113-A | novel isoxazolyl ether derivatives as GABA A α 5 PAM | 豪夫迈·罗氏有限公司 | 2019-06-21 | — | — | CN | claimed |
| CN-109890809-A | The substituted quinoxaline derivant of inhibitor as PFKFB | 默克专利股份公司 | 2019-06-14 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| CN-109415345-A | Broad spectrum influenza inhibitor based on pyridazinone | 豪夫迈·罗氏有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-108779076-A | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2018-11-09 | — | — | CN | claimed |
| CN-108059205-A | For the up-flow adsorptive reactor of orthophosphates in Adsorption waste water | 北京益清源环保科技有限公司 | 2018-05-22 | — | — | CN | claimed |
| CN-108026077-A | PHENOXYMETHYL DERIVATIVES | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | claimed |
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2004-07-22 | — | — | US | claimed |
| CN-1148355-C | Pyridazin-3-one derivatives and medicines containing the same | ������������ʽ���� | 2004-05-05 | — | — | CN | claimed |
| EP-1397340-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-03-17 | — | — | EP | claimed |
| WO-2002098850-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | claimed |
| CN-1341103-A | Pyridazin-3-one derivatives and drugs containing the same | KOWA CO (JP) | 2002-03-20 | — | — | CN | claimed |
| CN-1334805-A | Process for preparing pyridazin-2-one derivs. | SUMITOMO CHEMICAL CO (JP) | 2002-02-06 | — | — | CN | claimed |
| CN-1241175-A | Production of pyridazine herbicides | SUMITOMO CHEMICAL CO (JP) | 2000-01-12 | — | — | CN | claimed |
| CN-1240422-A | Production of pyridazine herbicides | SUMITOMO CHEMICAL CO (JP) | 2000-01-05 | — | — | CN | claimed |
| CN-1199732-A | Pyridazin-3-one derivatives and their use | SUMITOMO CHEMICAL CO (JP) | 1998-11-25 | — | — | CN | claimed |
| CN-1196353-A | Pyridazin-3-one derivatives and their use | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | CN | claimed |