Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242376 | 1.00 | ATM (0.32) | ATMUBE2MDCUN1D1 | |
| SCHEMBL2244743 | 0.87 | ATM (0.32) | ATM | |
| SCHEMBL4770750 | 0.79 | ATM (0.40) | ATM | |
| SCHEMBL1710341 | 0.79 | USP30 (0.31) | ATM | |
| SCHEMBL1710387 | 0.79 | USP30 (0.31) | ATM | |
| SCHEMBL1487188 | 0.77 | CTSK (0.39) | ATM | |
| SCHEMBL1265815 | 0.77 | CTSK (0.39) | ATM | |
| SCHEMBL743576 | 0.77 | CTSK (0.39) | ATM | |
| SCHEMBL16979518 | 0.74 | ATM (0.34) | ATM | |
| SCHEMBL25503913 | 0.73 | RET (0.44) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238135-A1 | NAPHTHYRIDIN-2(1H) -ONE COMPOUNDS USEFUL AS ANTIBACTERIALS | Glaxo Group Limited (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009090222-A1 | NAPHTHYRIDIN-2(1H) -ONE COMPOUNDS USEFUL AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |