Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAP2K4 | P45985 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 3/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072725 | 0.85 | KDR (0.59) | TTKKDM4EALDH1A1GAAMAPK10 | |
| SCHEMBL3020582 | 0.79 | TTK (0.56) | TTKKDM4EALDH1A1GAAMAPK10 | |
| SCHEMBL27968541 | 0.79 | TTK (0.56) | TTKKDM4EALDH1A1GAAMAPK10 | |
| SCHEMBL1997257 | 0.79 | TTK (0.56) | TTKKDM4EALDH1A1GAAMAPK10 | |
| SCHEMBL27591370 | 0.77 | KDM4E (0.46) | TTKKDM4EALDH1A1GAAMAPK10 | |
| SCHEMBL30065304 | 0.75 | PDPK1 (0.66) | KDM4EGAAAURKAFLT3MAPK9 | |
| SCHEMBL628649 | 0.75 | PDPK1 (0.66) | KDM4EGAAAURKAFLT3MAPK9 | |
| SCHEMBL5971620 | 0.75 | ALDH1A1 (0.56) | TTKKDM4EALDH1A1GAAMAPK10 | |
| SCHEMBL8830035 | 0.75 | TTK (0.51) | TTKKDM4EALDH1A1GAAMAPK10 | |
| SCHEMBL11815497 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227464-A1 | DERIVATIVES OF 1-[(IMIDAZOLIDIN-2-YL)IMINO)]INDAZOLE | Imperial Innovations Limited (GB) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009071906-A1 | DERIVATIVES OF 1-[(IMIDAZOLIDIN-2-YL)IMINO)]INDAZOLE | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-06-11 | — | — | WO | disclosed |