Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 11/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13000534 | 0.90 | AHR (0.37) | AHRCYP3A4MAPK1CYP1A2CYP2A6 | |
| SCHEMBL10311723 | 0.89 | AHR (0.40) | AHRCYP3A4MAPK1CYP1A2CYP2A6 | |
| SCHEMBL3724522 | 0.87 | CYP3A4 (0.41) | AHRCYP3A4MAPK1ALDH1A1TSHR | |
| SCHEMBL10524296 | 0.78 | AHR (0.41) | AHRCYP3A4MAPK1ALDH1A1TP53 | |
| SCHEMBL28744259 | 0.73 | CYP3A4 (0.53) | AHRCYP3A4MAPK1CYP1A2LMNA | |
| SCHEMBL29629138 | 0.73 | CYP3A4 (0.53) | AHRCYP3A4MAPK1CYP1A2LMNA | |
| SCHEMBL29857997 | 0.73 | CYP3A4 (0.53) | AHRCYP3A4MAPK1CYP1A2LMNA | |
| SCHEMBL28231062 | 0.70 | MAPT (0.35) | CYP3A4LMNAKDM4EMEN1ALOX15B | |
| SCHEMBL29586636 | 0.69 | AHR (0.55) | AHRCYP3A4MAPK1CYP1A2LMNA | |
| SCHEMBL28744278 | 0.69 | CYP3A4 (0.56) | AHRCYP3A4MAPK1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796456-B2 | Naphthalene diimide compounds | UNIVERSITY COLLEGE LONDON (GB) | 2014-08-05 | — | — | US | disclosed |
| US-8796456-B2 | Naphthalene diimide compounds | UNIVERSITY COLLEGE LONDON (GB) | 2014-08-05 | — | — | US | disclosed |
| US-8796456-B2 | Naphthalene diimide compounds | UNIVERSITY COLLEGE LONDON (GB) | 2014-08-05 | — | — | US | disclosed |
| EP-2227470-B1 | NAPHTHALENE DIIMIDE COMPOUNDS INTERACTING WITH G-QUADRPLEX REGIONS IN DNA | UNIV LONDON (GB) | 2014-03-05 | — | — | EP | disclosed |
| US-20100311739-A1 | Naphthalene Diimide Compounds | UNIVERSITY COLLEGE LONDON (GB) | 2010-12-09 | — | — | US | disclosed |
| US-20100311739-A1 | Naphthalene Diimide Compounds | UNIVERSITY COLLEGE LONDON (GB) | 2010-12-09 | — | — | US | disclosed |
| US-20100311739-A1 | Naphthalene Diimide Compounds | UNIVERSITY COLLEGE LONDON (GB) | 2010-12-09 | — | — | US | disclosed |
| EP-2227470-A1 | NAPHTHALENE DIIMIDE COMPOUNDS INTERACTING WITH G-QUADRUPLEX REGIONS IN DNA | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068916-A1 | NAPHTHALENE DIIMIDE COMPOUNDS INTERACTING WITH G-QUADRUPLEX REGIONS IN DNA | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2009-06-04 | — | — | WO | disclosed |
| WO-2009068916-A1 | NAPHTHALENE DIIMIDE COMPOUNDS INTERACTING WITH G-QUADRUPLEX REGIONS IN DNA | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2009-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311739-A1 | Naphthalene Diimide Compounds | NDC1, NUTF2, NDUFC2 | AHR 127/4885CYP3A4 821/4885MAPK1 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.