SCHEMBL3661690

SCHEMBL3661690

C#CCCCCOc1cccc(N(C)C(=O)c2ccc3ncccc3c2)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
DOT1L Q8TEK3 1/20 0.40
PLK1 P53350 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
NOTUM Q6P988 1/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
POLB P06746 2/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HPGD P15428 1/20 0.34
RECQL P46063 1/20 0.34
GPBAR1 Q8TDU6 1/20 0.34
CSF1R P07333 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3662163 0.99 ALOX15 (0.40) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3655615 0.99 ALOX15 (0.40) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3662575 0.97 ALOX15 (0.42) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3662578 0.95 ALOX15 (0.42) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3660738 0.91 ALOX15 (0.40) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3655971 0.90 ALOX15 (0.39) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3663834 0.90 ALOX15 (0.39) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3660238 0.90 ALOX15 (0.43) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3270396 0.90 ALOX15 (0.43) ALOX15HTTDOT1LPLK1TAS1R3
SCHEMBL3656299 0.88 ALOX15 (0.40) ALOX15HTTDOT1LPLK1TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed