Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930055 | 0.80 | HSD17B10 (0.56) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL11903083 | 0.80 | CYP3A4 (0.53) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL3313639 | 0.80 | PI4KA (0.57) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL532653 | 0.76 | HIF1A (0.49) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL6749169 | 0.76 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL7073449 | 0.74 | HTT (0.56) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL4419598 | 0.74 | PAK1 (0.60) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL30295447 | 0.73 | HSD17B10 (0.53) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL5384434 | 0.73 | CDC7 (0.59) | LMNATP53HSD17B10PRKACACDK2 | |
| SCHEMBL5433393 | 0.73 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231641-A2 | QUINOXALINE AND QUINOLINE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma, S.A. (BE) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009081105-A2 | QUINOXALINE AND QUINOLINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-07-02 | — | — | WO | disclosed |