SCHEMBL11903083

SCHEMBL11903083

OCc1ncnc2nc[nH]c12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.53
PI4KA P42356 2/20 0.52
PI4K2B Q8TCG2 2/20 0.52
PI4K2A Q9BTU6 2/20 0.52
PI4KB Q9UBF8 2/20 0.52
LRRK2 Q5S007 2/20 0.52
LMNA P02545 2/20 0.52
DRD3 P35462 1/20 0.52
XDH P47989 1/20 0.52
PDPK1 O15530 2/20 0.52
HSD17B10 Q99714 3/20 0.50
CDC7 O00311 1/20 0.50
DBF4 Q9UBU7 1/20 0.50
G6PD P11413 1/20 0.50
HIF1A Q16665 2/20 0.47
CYP1A2 P05177 1/20 0.47
CHEK1 O14757 1/20 0.47
AURKA O14965 1/20 0.47
CHEK2 O96017 1/20 0.47
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3661701 0.80 PI4KA (0.57) CYP3A4PI4KAPI4K2BPI4K2API4KB
SCHEMBL3313639 0.80 PI4KA (0.57) CYP3A4PI4KAPI4K2BPI4K2API4KB
SCHEMBL2930055 0.80 HSD17B10 (0.56) CYP3A4PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL25382 0.77 LMNA (0.57) CYP3A4PI4KAPI4K2BPI4K2API4KB
SCHEMBL5433393 0.77 PI4KA (0.44) CYP3A4PI4KAPI4K2BPI4K2API4KB
SCHEMBL532653 0.76 HIF1A (0.49) CYP3A4PI4KAPI4K2BPI4K2API4KB
SCHEMBL6749169 0.76 PI4KA (0.47) CYP3A4PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL6673817 0.75 LMNA (0.55) CYP3A4PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL1230632 0.75 LMNA (0.55) CYP3A4PI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL560393 0.75 PI4KA (0.59) CYP3A4PI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137453-A1 COMPOSITIONS, METHODS, KITS, AND INSTRUMENTS FOR ANALYZING RNA STRUCTURE NEW ENGLAND BIOLABS, INC. (US) 2025-06-26 WO disclosed
CN-115677807-A 6-position alpha-hydroxyalkylated purine compounds and methods for modification thereof 鲁东大学 2023-02-03 CN disclosed
US-20120202287-A1 Stem Cell Culture Methods ITI SCOTLAND LIMITED (GB) 2012-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202287-A1 Stem Cell Culture Methods KIT, SOX18, MCL1 CYP3A4 4330/4885PI4KA 4295/4885PI4K2B 4152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.