Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18212440 | 0.94 | LMNA (0.42) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL18205186 | 0.92 | LMNA (0.41) | ALDH1A1LMNACXCR4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18205189 | 0.92 | LMNA (0.41) | ALDH1A1LMNACXCR4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28658608 | 0.92 | LMNA (0.41) | ALDH1A1LMNACXCR4MEN1KMT2A | |
| SCHEMBL23374635 | 0.83 | LMNA (0.46) | ALDH1A1LMNACXCR4KDM4EMEN1 | |
| SCHEMBL4570867 | 0.83 | LMNA (0.46) | ALDH1A1LMNACXCR4KDM4EMEN1 | |
| SCHEMBL23374594 | 0.83 | LMNA (0.46) | ALDH1A1LMNACXCR4KDM4EMEN1 | |
| SCHEMBL9801414 | 0.80 | LMNA (0.51) | ALDH1A1LMNACXCR4KDM4EMEN1 | |
| SCHEMBL27209994 | 0.80 | LMNA (0.51) | ALDH1A1LMNACXCR4KDM4EMEN1 | |
| SCHEMBL23183278 | 0.78 | LMNA (0.43) | ALDH1A1LMNACXCR4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238103-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009095324-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-06 | — | — | WO | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0076072-B1 | SULPHONAMIDES | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1987-05-13 | — | — | EP | disclosed |
| US-4485108-A | ANTIARRHYTHMIA AGENTS | BEECHAM WUELFING GMBH & CO., KG (DE) | 1984-11-27 | — | — | US | disclosed |
| EP-0076072-A2 | Sulphonamides | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1983-04-06 | — | — | EP | disclosed |