Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 2/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536571 | 0.75 | FLT3 (0.39) | FLT3KDRGSK3BPRKD3PRKD1 | |
| SCHEMBL3653965 | 0.73 | HTR1D (0.41) | FLT3KDRGSK3BCDK7CDK9 | |
| SCHEMBL23536526 | 0.72 | FLT3 (0.34) | FLT3KDRGSK3BPRKD3PRKD1 | |
| SCHEMBL3227382 | 0.72 | FLT3 (0.36) | FLT3KDRGSK3BPRKD3PRKD1 | |
| SCHEMBL13424862 | 0.70 | CDK7 (0.34) | FLT3KDRGSK3BPRKD3PRKD1 | |
| SCHEMBL3622286 | 0.70 | FLT3 (0.35) | FLT3KDRGSK3BPRKD3PRKD1 | |
| SCHEMBL23536767 | 0.70 | KDR (0.34) | FLT3KDRGSK3BPRKD3PRKD1 | |
| SCHEMBL3660344 | 0.70 | CDK7 (0.36) | FLT3KDRGSK3BPRKD3PRKD1 | |
| SCHEMBL3657163 | 0.69 | JAK3 (0.36) | FLT3KDRGSK3BPRKD3PRKD1 | |
| SCHEMBL16801705 | 0.68 | PDE10A (0.49) | FLT3KDRGSK3BPRKD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024980-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |