Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 9/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653965 | 0.89 | HTR1D (0.41) | FLT3KDRGSK3BCAMKK2HTR1D | |
| SCHEMBL3657163 | 0.89 | JAK3 (0.36) | FLT3KDRGSK3BCAMKK2HTR1D | |
| SCHEMBL3660344 | 0.78 | CDK7 (0.36) | FLT3KDRGSK3BCAMKK2HTR1D | |
| SCHEMBL3216008 | 0.77 | JAK2 (0.44) | FLT3KDRGSK3BHTR1DCDK7 | |
| SCHEMBL3660456 | 0.76 | CDK7 (0.37) | FLT3KDRGSK3BCAMKK2HTR1D | |
| SCHEMBL3654875 | 0.76 | CDK7 (0.38) | FLT3KDRGSK3BCAMKK2HTR1D | |
| SCHEMBL3211442 | 0.70 | HTR1D (0.46) | HTR1DCDK7CDK9HTR1EHTR1A | |
| SCHEMBL3217516 | 0.70 | JAK3 (0.46) | FLT3KDRGSK3BHTR1DCDK7 | |
| SCHEMBL3661903 | 0.70 | HTR1D (0.44) | FLT3KDRGSK3BHTR1DCDK7 | |
| SCHEMBL3661901 | 0.70 | FLT3 (0.37) | FLT3KDRGSK3BCAMKK2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024980-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |