SCHEMBL3662210

SCHEMBL3662210

C=CCCCOc1cccc(NC)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.49
HPGD P15428 1/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
THRB P10828 1/20 0.42
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPK1 P28482 1/20 0.40
CYP2C19 P33261 1/20 0.40
GAA P10253 1/20 0.39
FAAH O00519 1/20 0.39
MAP2K7 O14733 1/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HTR1B P28222 1/20 0.38
SYK P43405 2/20 0.37
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3655354 0.95 APP (0.48) APPHPGDALDH1A1L3MBTL1THRB
SCHEMBL3655126 0.94 APP (0.47) APPHPGDALDH1A1THRBKDM4E
SCHEMBL3657171 0.94 APP (0.47) APPHPGDALDH1A1THRBKDM4E
SCHEMBL3659721 0.92 APP (0.50) APPHPGDALDH1A1THRBMAPK1
SCHEMBL3770881 0.83 APP (0.48) APPHPGDTHRBCYP1A2CYP2D6
SCHEMBL3656935 0.83 APP (0.48) APPHPGDTHRBCYP1A2CYP2D6
SCHEMBL17138189 0.83 ALDH1A1 (0.51) HPGDALDH1A1L3MBTL1CYP1A2CYP2D6
SCHEMBL3661946 0.82 GAA (0.53) APPALDH1A1L3MBTL1CYP1A2CYP2C19
SCHEMBL3660575 0.82 APP (0.47) APPTHRBCYP1A2CYP2D6MAPK1
SCHEMBL3661810 0.82 APP (0.47) APPTHRBCYP1A2CYP2D6MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 APP 2380/4885HPGD 4316/4885ALDH1A1 2906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.