Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2260815 | 0.96 | NR4A2 (0.48) | NR4A2FFAR1MAOBMRGPRX4GPR34 | |
| SCHEMBL2264260 | 0.86 | ESR2 (0.44) | NR1H2NR1H3RXRA | |
| SCHEMBL2260868 | 0.84 | MRGPRX4 (0.60) | NR4A2FFAR1MAOBMRGPRX4GPR34 | |
| SCHEMBL2260061 | 0.81 | MEN1 (0.65) | NR4A2FFAR1MAOBMRGPRX4GPR34 | |
| SCHEMBL2261371 | 0.76 | MAOB (0.51) | MAOBKMT2AMEN1 | |
| SCHEMBL27371605 | 0.75 | MEN1 (0.54) | NR4A2MAOBKMT2AMEN1 | |
| SCHEMBL3567254 | 0.74 | FFAR1 (0.56) | NR4A2FFAR1MRGPRX4GPR34FFAR4 | |
| SCHEMBL18736253 | 0.73 | MAPT (0.46) | NR4A2MAOBMRGPRX4FFAR4KMT2A | |
| SCHEMBL731203 | 0.73 | LMNA (0.62) | NR4A2MAOBMRGPRX4KMT2AMEN1 | |
| SCHEMBL18662327 | 0.73 | MRGPRX4 (0.54) | NR4A2FFAR1MAOBMRGPRX4GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234995-A1 | LEUKOTRIENE B4 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009077385-A1 | LEUKOTRIENE B4 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-06-25 | — | — | WO | disclosed |