Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23658037 | 0.94 | MAPT (0.53) | MAPTKDM4EGAATSHRACACB | |
| SCHEMBL10300112 | 0.85 | ACACB (0.52) | MAPTKDM4EGAATSHRACACB | |
| SCHEMBL10191904 | 0.80 | ACACB (0.46) | MAPTKDM4EGAATSHRACACB | |
| SCHEMBL28903834 | 0.77 | ACACB (0.44) | MAPTKDM4EGAATSHRACACB | |
| SCHEMBL13247286 | 0.76 | KDM4E (0.46) | MAPTKDM4EACACBMAOBMAOA | |
| SCHEMBL943860 | 0.75 | PKM (0.54) | MAPTKDM4EGAATSHRLMNA | |
| SCHEMBL3030269 | 0.75 | TSHR (0.46) | MAPTKDM4EGAATSHRACACB | |
| SCHEMBL4782387 | 0.73 | MAPT (0.51) | MAPTGAAACACBLMNAHTT | |
| SCHEMBL31399387 | 0.71 | MAPT (0.53) | MAPTKDM4EGAALMNAHTT | |
| SCHEMBL17365209 | 0.71 | MAPT (0.53) | MAPTKDM4EGAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235081-A1 | BLOCK POLYMER | Canon Kabushiki Kaisha (JP) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009090852-A1 | BLOCK POLYMER | CANON KABUSHIKI KAISHA (JP) | 2009-07-23 | — | — | WO | disclosed |