Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331740 | 0.92 | MTNR1A (0.46) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL3632623 | 0.84 | KCNH2 (0.42) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL592717 | 0.83 | MTNR1A (0.47) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL591010 | 0.83 | KCNH2 (0.43) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL592257 | 0.83 | KCNH2 (0.45) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL591392 | 0.81 | KCNH2 (0.42) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL3662327 | 0.81 | MTNR1A (0.57) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL592108 | 0.80 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL591651 | 0.80 | KCNH2 (0.48) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL703523 | 0.80 | KCNH2 (0.44) | KCNH2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146987-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008126024-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |