Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364546 | 0.81 | HDAC3 (0.64) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3459209 | 0.81 | ACHE (0.65) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| Benzene SCHEMBL27746310 | 0.80 | CYP2C9 (0.37) | L3MBTL1MEN1KMT2A | |
| SCHEMBL543404 | 0.80 | HDAC3 (0.67) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10762328 | 0.80 | ACHE (0.63) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6158231 | 0.80 | ACHE (0.63) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5179706 | 0.80 | ACHE (0.63) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2618044 | 0.80 | ACHE (0.68) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3662252 | 0.80 | ACHE (0.63) | ACHEEPHX1L3MBTL3L3MBTL1MGLL | |
| SCHEMBL3458901 | 0.80 | ACHE (0.63) | ACHEHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487444-B9 | USE OF PYRIDYL AMIDES AS INHIBITORS OF ANGIOGENESIS | ASTELLAS DEUTSCHLAND GMBH (DE) | 2010-07-21 | — | — | EP | claimed |
| EP-1487444-B1 | USE OF PYRIDYL AMIDES AS INHIBITORS OF ANGIOGENESIS | ASTELLAS DEUTSCHLAND GMBH (DE) | 2009-12-30 | — | — | EP | claimed |